Laser Therapy Studies
For more information, please see our Deep Tissue Laser Therapy brochure.
| laser_brochure.pdf |
Laser therapy is breakthrough in healing science. It is proven to be safe and effective. Below are just a few of the thousands of laser therapy clinical trials:
Lasers Heal: Chiropractors Could Benefit from This Technology
| laser_heal.pdf |
Laser Therapy Effective for Reducing Neck Pain
| laser_neckpain.pdf |
Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials
| laser_neck.pdf |
Class IV laser therapy; effective for back and neck/shoulder pain
| laser_backandneck.pdf |
Laser Therapy for Disc Herniations
| laser_discherniation.pdf |
Photobiomodulation of Pain in Carpal Tunnel Syndrome: Review of Seven Laser Therapy Studies
| laser_carpaltunnel.pdf |
Treating Neuropathies With Low-Intensity Laser Therapy
| laser_neuropathies.pdf |
Effects of Class IV Laser Therapy on Disease Impact and Function in Women with Fibromyalgia
| laser_fibromyalgia.pdf |
More studies:
Musculoskeletal
Shooshtari SM, Badiee V, Taghizadeh SH, Nematollahi AH, Amanollahi AH, Grami MT. The effects of low level laser in clinical outcome and neurophysiological results of carpal tunnel syndrome. Electromyogr Clin Neurophysiol. 2008; 48(5): 229-31.
Evcik D, Kavuncu V, Cakir T, Subasi V, Yaman M. Laser therapy in the treatment of carpal tunnel syndrome: a randomized controlled trial. Photomed Laser Surg. 2007 Feb;25(1):34-9.
Irvine J, Chong SL, Amirjani N, Chan KM. Double-blind randomized controlled trial of low-level laser therapy in carpal tunnel syndrome. Muscle Nerve. 2004 Aug;30(2):182-7.
Dincer U, Cakar E, Kiralp MZ, Kilac H, Dursun H. The Effectiveness of Conservative Treatments of Carpal Tunnel Syndrome: Splinting, Ultrasound, and Low-Level Laser Therapies. Photomed Laser Surg. 2009 Jan 26.
R Chow, M Johnson, R Lopes-Martins, J Bjordal. Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomized placebo or active-treatment controlled trials. Lancet 2009
Dundar U, Evcik D, Samli F, Pusak H, Kavuncu V. The effect of gallium arsenide aluminum laser therapy in the management of cervical myofascial pain syndrome: a double blind, placebo-controlled study. Clin Rheumatol. 2007 Jun;26(6):930-4.
Bjordal J, Joensen J, Bogen B, Lopes-Martins R, Johnson M, Iversen V, Couppe C, Chow R. an LLLT substitute NSAIDS, analgesics and steroid injections in arthritis, tendinopathies and muscle pain? A comparison of patient samples, efficacy and safety in randomized placebo-controlled trials. Photomed Laser Surg 2007; 24(4):131
Ali Gur, MD, Mehmet Karakoc, Remzi Cevik, Kemal Nas, Aysegul Jale Sarae, and Meral Karakoe. Efficacy of low power laser therapy and exercise on pain and functions in chronic low back pain. Lasers Surg Med 2003; 32: 233-238
Gür A, Karakoc M, Nas K, Cevik R, Sarac J, Ataoglu S. Effects of low power laser and low dose amitriptyline therapy on clinical symptoms and quality of life in fibromyalgia: a single-blind, placebo-controlled trial. Rheumatol Int. 2002 Sep;22(5):188-93.
Esmaeeli Djavid F, Mortazavi SMJ, BasirniaA, Sadeghipoor Roodsari G, Jamili P, Sheikhbahaee N, and Kaviani A. Low level laser therapy in musculoskeletal pain syndromes: pain relief and disability reduction. American Society for Laser Medicine and Surgery Abstracts, #152
Roberta T. Chow, Gillian Z. Heller, Les Barnsley. The effect of 300 mW, 830 nm laser on chronic neck pain: A double-blind, randomized, placebo-controlled study. Pain 124 (2006): 201-210.
Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Taufer D, Manfro DS, Rech M, Danna V, Grosselli D, Generosi RA, Marcos RL, Ramos L, Bjordal JM. Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. Lasers Med Sci. 2009 Nov;24(6):857-63.
Simunovic Z, Ivankovich AD, Depolo A. Wound healing of animal and human body sport and traffic accident injuries using low-level laser therapy treatment: a randomized clinical study of seventy-four patients with control group. J Clin Laser Med Surg. 2000 Apr;18(2):67-73.
Ng GY, Fung DT. Combining therapeutic laser and herbal remedy for treating ligament injury: an ultrastructural morphological study. Photomed Laser Surg. 2008 Oct;26(5):425-32.
Ng GY, Fung DT. The combined treatment effects of therapeutic laser and exercise on tendon repair. Photomed Laser Surg. 2008 Apr;26(2):137-41.
Stergioulas A, Stergioula M, Aarskog R, Lopes-Martins RA, Bjordal JM. Effects of low-level laser therapy and eccentric exercises in the treatment of recreational athletes with chronic achilles tendinopathy. Am J Sports Med. 2008 May;36(5):881-7.Cr
Inflammation
Campana VR, Moya M, Gavotto A, Spitale L, Soriano F, Palma. Laser therapy on arthritis induced by urate crystals. JA. Photomed Laser Surg, 2004;Dec;22(6):499-503.
Yamaura M, Yao M, Yaroslavsky I, Cohen R, Smotrich M, Kochevar IE. Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes. Laser Surg Med. 2009 Apr;41(4):282-90.
Hegedus B, Viharos L, Gervain M, Gálfi M. The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial. Photomed Laser Surg. 2009; 27(4): 577-84.
Kozlova IS, Tsurko VV, Piriazeva NA, Volkova ZI, Kariakina EV, Nikolaev VI, Mul'diiarov PIa. The mechanism of the action of laser therapy in rheumatoid arthritis. Ter Arkh. 1994;66(5):38-41.
Monteforte P, Baratto L, Molfetta L, Rovetta G. Low-power laser in osteoarthritis of the cervical spine. Int J Tissue React. 2003;25(4):131-6.
Campana V, Moya M, Gavotto A, Simes JC, Spitale L, Soriano F, Palma JA. He-Ne laser on microcrystalline arthropathies. J Clin Laser Med Surg. 2003 Apr;21(2):99-103.
Soriano F, Campana V, Moya M, Gavotto A, Simes J, Soriano M, Soriano R, Spitale L, Palma J. Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.Photomed Laser Surg. 2006 Apr;24(2):140-50.
Neurological
Rochkind S. Phototherapy in peripheral nerve regeneration: From basic science to clinical study. Neurosurg Focus. 2009;26(2):E8.
Rochkind S, Geuna S, Shainberg A. Phototherapy in peripheral nerve injury: effects on muscle preservation and nerve regeneration. Int Rev Neurobiol. 2009;87:445-64.
Rochkind, S., Leider-Trejo, L., Nissan, M., Shamir, M.V., Kharenko, O., Alon, M. Efficacy of 780-nm Laser Phototherapy on Peripheral Nerve Regeneration after Neurotube Reconstruction Procedure (Double-Blind Randomized Study) Phototherapy and Laser Surgery 2007 25(3): 137-143.
Byrnes, K.R., Waynant, R. W., Ilev, I.K., Wu, X., Barns, L., Smith, K., Heckert, R., Gerst, H., Anders, J.J. Light Promotes Regeneration and Functional Recovery and Alters the Immune Response after Spinal Cord Injury Lasers in Surgery and Medicine 2005 36: 171-185.
Rochkind, S, Drory, V., Alon, M, Nissan, M, Ouaknine. Laser Phototherapy (780 nm), a New Modality in Treatment of Long-Term Incomplete Peripheral Nerve Injury: A Randomized Double-Blind Placebo Controlled Study. Photomedicine and Laser Surgery 2007 25(5): 436-442.
Bone Regeneration
Kazem Shakouri S, Soleimanpour J, Salekzamani Y, Oskuie MR. Effect of low-level laser therapy on the fracture healing process. Lasers Med Sci. 2009 Apr 28.
Pereira CL, Sallum EA, Nociti FH Jr, Moreira RW. The effect of low-intensity laser therapy on bone healing around titanium implants: a histometric study in rabbits. Int J Oral Maxillofac Implants. 2009 Jan-Feb;24(1):47-51.
Blaya DS, Guimarães MB, Pozza DH, Weber JB, de Oliveira MG. Histologic study of the effect of laser therapy on bone repair. J Contemp Dent Pract. 2008 Sep 1;9(6):41-8.
AboElsaad NS, Soory M, Gadalla LM, Ragab LI, Dunne S, Zalata KR, Louca C. Effect of soft laser and bioactive glass on bone regeneration in the treatment of bone defects (an experimental study). Lasers Med Sci. 2009 Jul;24(4):527-33.
Stein E, Koehn J, Sutter W, Wendtlandt G, Wanschitz F, Thurnher D, Baghestanian M, Turhani D. Initial effects of low-level laser therapy on growth and differentiation of human osteoblast-like cells. Wien Klin Wochenschr. 2008;120(3-4):112-7.
Lymphadema
Kozanoglu E, Basaran S, Paydas S, Sarpel T. Efficacy of pneumatic compression and low-level laser therapy in the treatment of post mastectomy lymphoedema: a randomized controlled trial. Clin Rehabil. 2009 Feb;23(2):117-24.
Kaviani A, Fateh M, Nooraie RY, Alinagi-zadeh MR, Ataie-Fashtami L. Low-level laser therapy in management of post mastectomy lymphedema. Lasers Med Sci. 2006 Jul;21(2):90-4.
Carati CJ, Anderson SN, Gannon BJ, Piller NB. Treatment of post mastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial. Cancer. 2003 Sep 15;98(6):1114-22.
Herpes Simplex/Zoster
Marotti J, Aranha AC, Eduardo Cde P, Ribeiro MS. Photodynamic therapy can be effective as a treatment for herpes simplex labialis. Photomed Laser Surg. 2009 Apr; 27(2):357-63.
Navarro R, Marquezan M, Cerqueira DF, Silveira BL, Corrêa MS. Low-level-laser therapy as an alternative treatment for primary herpes simplex infection: a case report J Clin Pediatr Dent. 2007 Summer; 31(4):225-8.
Schindl A, Neumann R. Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study. J Invest Dermatol 1999 Aug; 113(2):221-3.
Iijima K, Shimoyama N, Shimoyama M, Mizuguchi T. Evaluation of analgesic effect of low-power He:Ne laser on postherpetic neuralgia using VAS and modified McGill pain questionnaire. J Clin Laser Med Surg. 1991 Apr; 9(2):121-6.
Wounds, Burns and Pain Control
Taı's Zanin, Fatima Zanin, Artur Aburad Carvalhosa, Paulo Henrique de Souza Castro, Marcos Tadeu Pacheco, Iriana Carla Junqueira Zanin, and Aldo Brugnera Junior Use of 660-nm Diode Laser in the Prevention and Treatment of Human Oral Mucositis Induced by Radiotherapy and Chemotherapy. Photomed Laser Surg 2010; 28(2):233-237
Byrnes KR, Barna L, Chenault VM, Waynant RW, Ilev IK, Longo L, Miracco C,Johnson B, Anders JJ. Photobiomodulation improves cutaneous wound healing in an animal model of type II diabetes. Photomed Laser Surg. 2004 Aug;22(4):281-90.
Medrado AR, Pugliese LS, Reis SR, Andrade ZA. Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts. Lasers Surg Med. 2003;32(3):239-44.
Hopkins JT, McLoda TA, Seegmiller JG, David Baxter G. Low-level laser therapy facilitates superficial wound healing in humans: a triple-blind, sham-controlled study. J Athl Train. 2004 Sep;39(3):223-229.
Woodruff LD, Bounkeo JM, Brannon WM, Dawes KS, Barham CD, Waddell DL, Enwemeka CS. The efficacy of laser therapy in wound repair: a meta-analysis of the literature.Photomed Laser Surg. 2004Jun;22(3):241-7.
Herascu N, Velciu B, Calin M, Savastru D, Talianu C. Low-level laser therapy (LLLT) efficacy in post-operative wounds. Photomed Laser Surg. 2005 Feb;23(1):70-3.
Enwemeka CS, Parker JC, Dowdy DS, Harkness EE, Sanford LE, Woodruff LD. The efficacy of low-power lasers in tissue repair and pain control: a meta-analysis study. Photomed Laser Surg. 2004 Aug;22(4):323-9.
Ribeiro MS, Da Silva Dde F, De Araujo CE, De Oliveira SF, Pelegrini CM, Zorn TM, Zezell DM. Effects of low-intensity polarized visible laser radiation on skin burns: a light microscopy study. J Clin Laser Med Surg. 2004 Feb;22(1):59-66.
Gaida K, Koller R, Isler C, Aytekin O, Al-Awami M, Meissl G, Frey M. Low level laser therapy--a conservative approach to the burn scar? Burns. 2004 Jun;30(4):362-7.
Dermatological
Lask, G., Fournier, N., Trelles, M., Elman, M., Scheflan, M., Slatkine, M., Naimark, J., Harth, Y. The utilization of non thermal blue (405-425 nm) and near infrared (850-890 nm) light in aesthetic dermatology and surgery – a multicenter study. Journal of Cosmetic and Laser Therapy 2005; 7: 163-170.
Robert A. Weiss, MD, David H. McDaniel, MD, Roy G. Geronemus, MD, and Margaret A. Weiss, MD. Clinical Trial of a Novel Non-Thermal LED Array for Reversal of Photoaging: Clinical, Histologic, and Surface Profilometric Results. Lasers Surg. Med. 2005; 36:85–91.
Elman M, Lebzelter J. Light therapy in the treatment of acne vulgarisDermatol Surg. 2004 Feb;30(2):139-46.
P. Papageorgious, A. Katsambas, A. Chu Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris. British Journal of Dermatology 2000: 142: 973-978.
Lask, G., Fournier, N., Trelles, M., Elman, M., Scheflan, M., Slatkine, M., Naimark, J., Harth, Y. The utilization of non thermal blue (405-425 nm) and near infrared (850-890 nm) light in aesthetic dermatology and surgery – a multicenter study. Journal of Cosmetic and Laser Therapy 2005; 7: 163-170.